Intensive care unit acquired weakness

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Clinical review: intensive care unit acquired weakness.

A substantial number of patients admitted to the ICU because of an acute illness, complicated surgery, severe trauma, or burn injury will develop a de novo form of muscle weakness during the ICU stay that is referred to as "intensive care unit acquired weakness" (ICUAW). This ICUAW evoked by critical illness can be due to axonal neuropathy, primary myopathy, or both. Underlying pathophysiologic...

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Intensive-care-unit-acquired muscle weakness.

Neuromuscular abnormalities culminating in skeletal-muscle weakness occur very commonly in critically ill patients. Intensive-care-unit (ICU) acquired neuromuscular abnormalities are typically divided into 2 discrete classes: polyneuropathy and myopathy. However, it is likely that these 2 entities commonly coexist, with myopathy being the most common cause of weakness. Major risk factors for IC...

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Intensive care unit acquired weakness : measuring recovery from critical illness

Introduction Intensive care unit-acquired weakness (ICU-AW) is a common consequence of critical illness, affecting between 25% and 100% of critical care patients.1,2 ICU-AW is a syndrome encompassing myopathic, neuropathic and atrophic changes, which clinically presents as profound weakness. Its presence can hinder and dictate the course of recovery, leading to protracted weaning from mechanica...

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Molecular mechanisms of intensive care unit-acquired weakness.

Intensive care unit-acquired weakness (ICUAW) is an increasingly recognised and important clinical consequence of critical illness. It is associated with significant morbidity and mortality. The aetiology of this disease is not well understood. The purpose of this article is to review our understanding of the molecular pathogenesis of ICUAW in the context of current knowledge of clinical risk f...

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Physiotherapy management of intensive care unit-acquired weakness.

[Hodgson CL, Tipping CJ (2016) Physiotherapy management of intensive care unit-acquired weakness.Journal of Physiotherapy63: 4-10].

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ژورنال

عنوان ژورنال: Medicine

سال: 2020

ISSN: 0025-7974,1536-5964

DOI: 10.1097/md.0000000000021926